Our Directors believe that the worldwide demand for natural drugs is increasing with the public perception of higher safety and lower side effects of natural drugs as compared to chemical drugs. To the best of our Directors' knowledge, the current worldwide annual sales of natural drugs amount to approximately US$16 billion and such sales volume is expected to grow at approximately 10% per annum for the next two years.
The development of new drugs with new chemical compounds require substantial investment. Accordingly, in the recent years, attention has been focused on the research of drugs with new formulations as the development expenses incurred are only approximately one tenth of that for new drugs.
Our Directors believe that the R&D of drugs with new formulations is becoming a major trend in the global pharmaceutical industry, particularly in the fields of advanced drug delivery technologies such as sustained release system and controlled release drug delivery system. To the best of our Directors' knowledge, the global revenue of pharmaceutical products which utilise advanced drug delivery technology reached US$38 billion in 2002. Our Directors estimate that this market will grow at an average rate of 28% per annum between 2003 and 2007.
Medical advances and technological development coupled with an increased public awareness on the importance of healthcare have led to a steady growth of the PRC pharmaceutical market. This has created considerable opportunities for the pharmaceutical industry in the PRC. Going forward, our Directors estimate that between 2001 and 2005, the demand for pharmaceutical drugs in the PRC would grow at an average rate of 12% annually, reaching RMB218 billion by 2005.
Our Directors believe that the following will be the main factors which will sustain the expected growth of the pharmaceutical industry in the PRC: